Tag: Various positive properties

Fullerenols (polyhydroxylated fullerene C60) are nanomaterial with potentially broad applicability in biomedical sciences with high antioxidant ability, thus, we investigated the radioprotecting potential of fullerenol C60(OH)36#nbsp;on human erythrocytes irradiated by high-energy electrons of 6 MeV. The results demonstrate that C60(OH)36#nbsp;at concentration of 150 μg/mL protects the erythrocytes against the radiation-induced hemolysis (comparing to non-protected cells,… Continue reading Fullerenol C 60(OH) 36 protects human erythrocyte membrane against high-energy electrons

Biomineralization is a typical methodology developed by nature to produce calcium-based materials. A method mimicking this process has nowadays become popular for the preparation of artificial organic-inorganic hybrids. Here, Cu3(PO4)2#nbsp;crystals with a flowerlike morphology have been prepared using water-soluble derivatives of fullerene C60#nbsp;as templates. In a typical system, flowerlike crystals of Cu3(PO4)2#nbsp;(denoted FLCs-Cu) were obtained… Continue reading Fullerene-Directed Synthesis of Flowerlike Cu 3(PO 4) 2 Crystals for Efficient Photocatalytic Degradation of Dyes

The leaf is a prime example of a material converting waste (CO2#nbsp;) into value with maximum sustainability. As the most important constituent, it contains the coupled photosystems II and I, which are imbedded in the cellular membrane of the chloroplasts. Can key functions of the leaf be packed into soap? We present next-generation surfactants that… Continue reading Molecular Semiconductor Surfactants with Fullerenol Heads and Colored Tails for Carbon Dioxide Photoconversion

Application of dilational surface rheology, surface tensiometry, ellipsometry, Brewster angle, and transmission electron and atomic force microscopies allowed the estimation of the structure of the adsorption layer of a fullerenol with a large number of hydroxyl groups, C60(OH)#nbsp;X#nbsp;( X = 30 ± 2). The surface properties of fullerenol solutions proved to be similar to the… Continue reading Dynamic Surface Properties of Fullerenol Solutions

In an attempt to understand the possibility of applications of the fullerene-based systems for transporting various polar compounds like hexamethonium through the blood-brain barrier, we studied the influence of a series of derivatives of fullerene C60#nbsp;in the form of salts with hexamethonium bis-anion, namely the adducts of fullerenols with 6-aminohexanoic acid (IEM-2197), and two bis-adduct… Continue reading The mechanisms of action of water-soluble aminohexanoic and malonic adducts of fullerene C 60 with hexamethonium on model lipid membranes

With the wide application of fullerenols in biomedicine, their environmental exposure risks and toxicity to organisms have been extensively studied. However, there is still a lack of knowledge about the distribution of fullerenols in organisms as an important aspect of their mechanism of toxicity. High-resolution matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) is an emerging… Continue reading Visualization of the tissue distribution of fullerenols in zebrafish (Danio rerio) using imaging mass spectrometry

In this work, fullerenols were found to be able to enhance the ECL signals of the luminol and H2O2#nbsp;system and were employed for the first time as a reducing, catalyzing, and stabilizing agent in the one-step fast synthesis of fullerenols@AuNPs in only 5 min. First, the prepared fullerenols@AuNPs were applied to fabricate a label-free immunosensor… Continue reading Electrochemiluminescent Detection of Proteins Based on Fullerenols Modified Gold Nanoparticles and Triple Amplification Approaches

In aquatic organisms, dietary exposure to nanomaterials is not only one of the important uptake pathways, but it is also one method to assess the transmission risk of the food chain. To address this concern, we quantitatively investigated the accumulation and depuration of fullerenols in the tissues of zebrafish after exposure to fullerenols-contaminated Daphnia magna.… Continue reading Bioaccumulation, biodistribution，and depuration of 13 C-labelled fullerenols in zebrafish through dietary exposure

Background:#nbsp;Multidrug-resistant (MDR) bacterial strain is a serious medical problem. Methicillin-resistant#nbsp;Staphylococcus aureus#nbsp;(MRSA) is resistant to many antibiotics and is often associated with several diseases such as arthritis, osteomyelitis, and endocarditis. The development of an alternative treatment for eliminating MDR bacteria such as MRSA has attracted a considerable amount of research attention. Moreover, the development of a… Continue reading Two-Photon Photoexcited Photodynamic Therapy with Water-Soluble Fullerenol Serving as the Highly Effective Two-Photon Photosensitizer Against Multidrug-Resistant Bacteria

Novel mixed matrix dense and supported membranes based on biopolymer sodium alginate (SA) modified by fullerenol were developed. Two kinds of SA-fullerenol membranes were investigated: untreated and cross-linked by immersing the dry membranes in 1.25 wt % calcium chloride (CaCl2) in water for 10 min. The structural and physicochemical characteristics features of the SA-fullerenol composite… Continue reading Novel Mixed Matrix Sodium Alginate-Fullerenol Membranes: Development, Characterization, and Study in Pervaporation Dehydration of Isopropanol

Traditional approaches for nucleic acids detection require prior amplification of target genes, while nanomaterials-aided DNA biosensors are very magnificent but still suffer from the nanomaterial acquirement and limited sensitivity (above picomolar level). Herein, fullerenol C60(OH)25, a representative fullerene derivative, was employed as a photoelectrochemical (PEC) nanoprobe to achieve discrimination and ultrasensitive detection of amplification-free single-stranded… Continue reading Fullerenol as a photoelectrochemical nanoprobe for discrimination and ultrasensitive detection of amplification-free single-stranded DNA

Helicobacter pylori#nbsp;(H. pylori) eradication by antibiotics and proton pump inhibitor treatment is limited by the low pH microenvironment in the stomach and can lead to antibiotic resistance. We fabricated fullerenol nanoparticles (FNPs) with varied chemical structures responding to a pinacol rearrangement of vicinal hydroxyl to form carbonyls in low pH environments. An obvious increase in… Continue reading Fullerenol Nanoparticles Eradicate Helicobacter pylori via pH-Responsive Peroxidase Activity